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Try out PMC Labs and tell us what you think. Learn More. Orgasm is one of the most intense pleasures attainable to an organism, yet its underlying mechanisms remain poorly understood. On the basis of existing literatures, this article introduces a novel mechanistic model of sexual stimulation and orgasm.
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Try out PMC Labs and tell us what you think. Learn More. Human female orgasm is a vexed question in the field while there is credible evidence of cryptic female choice that has many hallmarks of orgasm in other species. Our initial goal was to produce a proof of concept for allowing females to study an aspect of infertility in a home setting, specifically by aligning the study of human infertility and increased fertility with the study of other mammalian fertility.
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Normally, semen exits the penis when a man ejaculates. Retrograde ejaculation causes some semen to travel backward into the bladder. The ejaculate can move out of the penis because a small muscle, called the bladder sphincter, closes the opening to the bladder, preventing the semen from entering the bladder. When the bladder sphincter does not work correctly, the bladder may not close completely, which can cause ejaculate to travel into the bladder rather than coming out of the penis.
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